Performance of herbal mouth rinse in the prevention of oral infections

Abstract

Objectives: To evaluate the performance of an herbal Sanative® solution in the postoperative of tooth extractions. Methods: This randomized, crossover, clinical trial was conducted in 30 patients who presented an indication for simple tooth extractions on opposite sides. After surgery, patients received 150 mL of chlorhexidine digluconate 0.12% and an herbal Sanative® for use in the region for seven days after oral surgery. To evaluate the analgesic effect of both protocols, we used a 10 cm visual analog scale (VAS) and postoperative analgesic consumption. To assess the prevalence of postoperative complications, we examined the presence of bleeding, hyperemia, or necrosis seven days after oral surgery. Results: No difference (Wilcoxon test, p> 0.05) was found between the treatments regarding VAS score in the period of 24 hours or 7 days after surgery or regarding postoperative analgesic consumption (Wilcoxon test, p=0.5536). In the period of 7 days, there was a decrease in the VAS score of both groups. However, only chlorhexidine showed difference (Wilcoxon, p= 0.0178). There was no difference between treatments considering bleeding, hyperemia, and necrosis (Fisher’s exact test, p= 0.9656). Conclusion: Sanative® presented equal efficacy to chlorhexidine and demonstrated to be a valuable option for the prevention of postoperative complications.